Introduction: Numerous studies have referred to the prediction of Alzheimer's disease based on risk factors, but there are insufficient studies that identify or characterize these factors in the pregeriatric population.

Objective: To characterize the risk factors for Alzheimer's disease in a pre-geriatric population in a medical office.

Methods: An observational, descriptive, cross-sectional study was carried out from January to June 2023. From a study universe of 165 patients aged 45 to 59 years, a sample of 140 was formed, by non-probabilistic sampling and at the discretion of the authors. A database was created and processed using descriptive statistics, through mathematical calculations for distribution of absolute and relative frequencies.

Results: The age group of 55-59 years predominated with 42,15 % and the female sex with 57,14 %, where there was a greater frequency and concurrence of risk factors. Sedentary lifestyle stood out at 56,43 %, poor economic situation at 42,14 % and social isolation at 39,29 %. The upper middle level reached 47,14 %. Patients at risk between 50 and 59 years old represented 75 %. More than 50 % have three or more risks.

Conclusions: Several of the main risk factors for Alzheimer's disease occur with high frequency and concurrence in patients under 60 years of age, who can still be operated on, taking advantage of their high educational level.