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Najwa Mohammed Jameel

University of Basrah, Iraq

Presentation Title:

Production, purification and characterization of terpenes isolated from two new strains of yeasts in Iraq and study of their antiparasitic activity

Abstract

The current study was  included isolation and identification of yeasts from  five sediments soil samples from Al-Faw and Shatt al-Arab in Basrah provinces. Collected the soil samples during fallow period 1-1-2021 to 1-6-2022, in the primary isolation dilution method was used for cultured soil samples, used two crud colonies filtration. Two types of terpenes (T1,T2) were purified from culture filtrates  of both species Cystobasidium benthicum C.minutum separately.The first step of purification was included thin layer chromatograoh then column chromatography. Beside of cytotoxicity test was revealed no toxic effect for both terpenes at 0.2 gm / ml concentration. Given the importance of hydatid cyst disease on the health of the individual and society and the epidemiology of the disease in Iraq and the economic losses it causes and the collateral damage of chemically manufactured drugs and their high cost, the current study aimed to search for more treatments that limit the vitality of the larval stages of the parasite, so it was done antiparasite activity for both terpenes were performed against Echinococcus granulosus the results showed the T1 more activity against parasite compared with T2. Finally, the two terpenes were identified using ultra violet and infra-red spectroscopy therefore the results were showed the terpenes nature of both toxins, the important active groups were determined in the structure of the two isolated terpenes. 

Biography

Najwa Mohammed Jameel is a distinguished academic and researcher in the field of biological sciences, with a particular focus on medical mycology and biotechnology. She graduated from the College of Science at the University of Basra in 2000 with a degree in Life Sciences. Dr. Jameel's academic journey continued with a Master's degree in Medical Mycology in 2005, followed by a Ph.D. in Biotechnology - Mycology in 2020. In recognition of her outstanding contributions to the scientific community, she was awarded the title of Professor in 2019. Over the years, Dr. Jameel has made significant contributions to the fields of life sciences and biotechnology through her research, teaching, and mentorship. Jameel has supervised four PhD students and one Master's student, guiding them in their research and helping shape the next generation of scientists. She has been actively involved in the academic community, participating in 103 workshops and publishing 53 research papers in both international and local scientific journals. Additionally, she authored a book on a specialized topic within her field. Her research expertise has been presented at 10 scientific conferences and she has participated in 7 patent exhibitions, where she has been awarded gold, silver, and bronze medals for her innovative contributions. She has also been honored with the Excellence Shield for her remarkable achievements. Her scientific work has led to three registered patents, notably in the area of quality control and calibration equipment, which she developed in collaboration with the Ministry of Planning in Iraq.