The pandemic of COVID-19 is the largest in this century. Aside from the acute infection, some of the patients have been challenged with a complication that is known as long COVID-19. The symptoms of long COVID-19 are extensive and diverse. Long COVID-19 continues to plague many patients post-COVID-19 infection. No universal treatment has been found. This study presents four patients who suffered from long COVID-19. Each patient presented with a different and diverse symptom of long COVID-19. Each of the patient's symptoms resolved or greatly improved upon taking the anti-viral drug acyclovir. Acyclovir has been in use since 1981 and is generally considered safe. A novel theory as to the pathophysiology of long COVID-19 symptoms and the result of a new treatment is presented. The purpose of this study is to provide a foundation for much bigger studies and useful resources for further testing to halt long COVID-19.

Dr. Robert M. Beatty is a neurosurgeon in Overland Park, Kansas and is affiliated with multiple hospitals in the area, including Research Medical Center and Overland Park Regional Medical Center. He received his medical degree from University of Utah School of Medicine and has been in practice for more than 20 years. He has expertise in treating spinal fusion, neck pain and spine problems, among other conditions - see all areas of expertise. He accepts Medicare, Aetna, Humana, Cigna, Blue Cross, United Healthcare - see other insurance plans accepted. He is highly recommended by patients.